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And low levels can accelerate the aging process

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By carefully selecting and balancing the types of fatty acids in HFDs, it may be possible to reduce the tumor-promoting effects of obesity while simultaneously increasing immune responses against tumors

However, also dietary/drinking water Se excess is associated with infertility and testicular degeneration in experimental animals, related to higher GPX4 and lactate dehydrogenase activity and higher hydrogen selenide production, and reduced spermatozoa motility, concentration, and typical spermatozoa morphological defects (with the fusion of two midpieces, vacuolization of the cytoplasm, and twisted tails) (85, 105, 117, 169)